NIH SBIR/STTR budget caps — the numbers, and where to verify them.
SBA publishes statutory guideline award levels that adjust annually. NIH institutes and centers then set their own limits per NOFO — some at the guideline, some higher under approved waiver topics. Use this page for orientation. Use the linked NIH SEED and SBA pages for the number you cite in a budget.
These figures adjust annually and vary by IC. Always confirm the current cap against the live SBA/NIH SEED figure for your target IC and the specific NOFO you are answering. A related NIH Guide Notice overrides the NOFO; the NOFO overrides the Application Guide; SBA statutory guidelines set the ceiling absent a waiver.
- Phase IR43 (SBIR) / R41 (STTR)typically 6–12 months (SBIR); longer with justification. STTR guideline up to 1 yearUp to $700K at some ICs; many ICs at the SBA guidelineprior level: $314,363Under the 2026 parent solicitations, Phase I runs up to $700,000 at several ICs (including NCI, NIA, NIAID, NIGMS, NIMH, NINDS, NCCIH); other ICs cap at the SBA guideline. Approved waiver topics may exceed these amounts. Confirm the ceiling for your IC in the PA-27-100 / PA-27-102 IC table before budgeting.
- Phase IIR44 (SBIR) / R42 (STTR)1 – 3 yearsUp to $3M at some ICs; many ICs at the SBA guidelineprior level: $2,095,748Under the 2026 parent solicitations, Phase II runs up to $3,000,000 at several ICs (including NHLBI, NIA, NIAID, NIDCD, NIGMS, NIMH, NINDS); other ICs cap at the SBA guideline. Example line items from the IC table: NCI $700,000 Phase I / $2,500,000 Phase II; NHLBI $400,000 Phase I / $3,000,000 Phase II. Direct-to-Phase-II (D2P2) uses the same cap when the IC participates.
- Commercialization Readiness Pilot (CRP)SB1 / R44 CRP supplementVaries by IC; typically 1 – 2 yearsSee PAR-27-098 for current CRP levels.Post-Phase-II bridge for regulatory, manufacturing scale-up, or partnering activities. Availability, cap, and mechanism vary by IC and NOFO — see PAR-27-098.
- Phase IIB — Strategic BreakthroughR44 Phase IIB (IC-specific)Varies (often 2 – 3 years)IC-set; can significantly exceed statutory levelsFollow-on Phase II awards for programs still requiring substantial R&D — e.g. NCI SBIR Phase IIB Bridge Awards can reach $4M+ and often expect substantial (~1:1) third-party matching funds — verify the specific NCI Bridge NOFO.
Everything directly incurred by the project. Subawards to the STTR research partner count toward direct costs and toward the 30% partner-work minimum.
If you have a negotiated indirect rate with a federal cognizant agency, use it. If not, SBIR/STTR applicants may use a de minimis rate — as of the 2024 Uniform Guidance revision, up to 15% of modified total direct costs — without formal negotiation.
Distinct from indirect costs. Not tied to actual profit, not audited as profit — a fixed allowance recognized by SBA for SBIR/STTR small businesses. Cap is 7% for both Phase I and Phase II.
TOTAL AWARD = DIRECT + INDIRECT + FEE. THE STATUTORY GUIDELINE IS THE TOTAL, INCLUSIVE OF ALL THREE.
NIH institutes and centers can set award ceilings above the SBA statutory guideline only for topics SBA has approved for waiver. Several ICs — including NCI, NIAID, NHLBI, NIDA, and NINDS — maintain waiver-topic lists that permit Phase I above the guideline (commonly $400K, occasionally higher) and Phase II above the guideline (commonly $2.5M–$3M). Always check the NOFO you are answering; the waiver topics are enumerated there.
NIH's official small-business funding hub publishes the current statutory guideline award levels for Phase I, Phase II, and CRP — and lists ICs with approved waiver topics that permit higher budgets on specific topics. This is the number to cite when you're writing a budget.
The 2026 SBIR parent solicitation — the authoritative source for the per-IC ceiling that applies to your budget.
SBA sets the statutory guideline levels and adjusts them for inflation annually. Waiver topics that permit higher awards must be approved by SBA on a topic-by-topic basis; agencies cannot unilaterally exceed the statutory guideline.
Direct-cost vs. F&A (indirect) treatment, allowable-cost principles, and the SBIR/STTR fee are documented in the NIH Grants Policy Statement. This is the reference NIH grants management specialists work from during Just-In-Time review.
Small businesses without a negotiated indirect rate may use the federal de minimis F&A rate. The 2024 revision to 2 CFR 200 raised the de minimis ceiling; confirm the current rate against the live regulation before submitting a budget.
We do not print a "the cap is $X" claim without a link. SBA adjusts these levels for inflation each year and ICs publish waiver topics independently. If the number you need is time-sensitive — a budget going into eRA Commons tomorrow — open the NIH SEED link above and use the figure printed there, then cross-check the specific NOFO you are answering.
